An infrared optical pacing system for screening cardiac electrophysiology in human cardiomyocytes.

Human cardiac myocytes derived from pluripotent stem cells (hCM) have invigorated interest in genetic disease mechanisms and cardiac safety testing; however, the technology to fully assess electrophysiological function in an assay that is amenable to high throughput screening has lagged. We describe...

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Bibliographic Details
Main Authors: Matthew T McPheeters, Yves T Wang, Andreas A Werdich, Michael W Jenkins, Kenneth R Laurita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0183761