Monoconjugation of Human Amylin with Methylpolyethyleneglycol.

Amylin is a pancreatic hormone cosecreted with insulin that exerts unique roles in metabolism and glucose homeostasis. The therapeutic restoration of postprandial and basal amylin levels is highly desirable in diabetes mellitus. Protein conjugation with the biocompatible polymer polyethylene glycol...

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Bibliographic Details
Main Authors: Tháyna Sisnande, Luiz Henrique Guerreiro, Raquel R Braga, Luana Jotha-Mattos, Luiza C S Erthal, Priscilla Tinoco, Bruno M Ferreira, Luís Maurício T R Lima
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4598023?pdf=render