Efficient Generation of Human Embryonic Stem Cell-Derived Corneal Endothelial Cells by Directed Differentiation.

AIM:To generate human embryonic stem cell derived corneal endothelial cells (hESC-CECs) for transplantation in patients with corneal endothelial dystrophies. MATERIALS AND METHODS:Feeder-free hESC-CECs were generated by a directed differentiation protocol. hESC-CECs were characterized by morphology,...

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Bibliographic Details
Main Authors: Kathryn L McCabe, Noelia J Kunzevitzky, Brian P Chiswell, Xin Xia, Jeffrey L Goldberg, Robert Lanza
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4686926?pdf=render