microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells.

microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells.

Animal microRNAs (miRNAs) typically regulate gene expression by binding to partially complementary target sites in the 3' untranslated region (UTR) of messenger RNA (mRNA) reducing its translation and stability. They also commonly induce shortening of the mRNA 3' poly(A) tail, which contri...

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Bibliographic Details
Main Authors: Traude H Beilharz, David T Humphreys, Jennifer L Clancy, Rolf Thermann, David I K Martin, Matthias W Hentze, Thomas Preiss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19710908/pdf/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/19710908/pdf/?tool=EBI

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