Determination of Deleterious SNPs in APH1A Gene Related to Alzheimers Disease by In Silico Methods
Alzheimers disease (AD) is a progressive neurodegenerative disease characterized by pathological accumulation of ?-amyloid (A?) senile plaques and neurofibrillary tangles. ?-secretase produces the amyloid ? peptide (A?), which causes AD. ?-secretase is a macromolecular complex and the protein encode...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Suleyman Demirel University
2019-08-01
|
| Series: | Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi |
| Online Access: | http://dergipark.org.tr/tr/download/article-file/784617 |