Determination of Deleterious SNPs in APH1A Gene Related to Alzheimers Disease by In Silico Methods
Alzheimers disease (AD) is a progressive neurodegenerative disease characterized by pathological accumulation of ?-amyloid (A?) senile plaques and neurofibrillary tangles. ?-secretase produces the amyloid ? peptide (A?), which causes AD. ?-secretase is a macromolecular complex and the protein encode...
Main Authors: | Ebru OZKAN OKTAY, TuGba KAMAN, Omer Faruk KARASAKAL, Korkut ULUCAN, Muhsin KONUK, Nevzat TARHAN |
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Format: | Article |
Language: | English |
Published: |
Suleyman Demirel University
2019-08-01
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Series: | Süleyman Demirel Üniversitesi Fen Bilimleri Enstitüsü Dergisi |
Online Access: | http://dergipark.org.tr/tr/download/article-file/784617 |
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