Association between the polymorphism rs3217927 of CCND2 and the risk of childhood acute lymphoblastic leukemia in a Chinese population.

Association between the polymorphism rs3217927 of CCND2 and the risk of childhood acute lymphoblastic leukemia in a Chinese population.

CyclinD proteins, the ultimate recipients of mitogenic and oncogenic signals, play a crucial role in cell-cycle regulation. CyclinD2, one of the cyclinD family, is overexpressed in T-acute lymphoblastic leukemia (ALL) and B-cell chronic lymphocytic leukemia and involved in the pathogenesis of leukem...

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Bibliographic Details
Main Authors: Heng Zhang, Yan Zhou, Yaoyao Rui, Yaping Wang, Jie Li, Liuchen Rong, Meilin Wang, Na Tong, Zhengdong Zhang, Jing Chen, Yongjun Fang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3990598?pdf=render

Internet

http://europepmc.org/articles/PMC3990598?pdf=render

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