Lack of association between methylenetetrahydrofolate reductase C677T polymorphism, HPV infection and cervical intraepithelial neoplasia in Brazilian women

Lack of association between methylenetetrahydrofolate reductase C677T polymorphism, HPV infection and cervical intraepithelial neoplasia in Brazilian women

Abstract Background Cervical cancer has high prevalence and mortality rates in worldwide female population. Persistent infection by high-risk Human Papillomavirus (hr-HPV) is the main cause of this cancer. However, many environmental, genetical, and epigenetical cofactors can modulate viral infectio...

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Bibliographic Details
Main Authors: Nayara Nascimento Toledo Silva, Adriano de Paula Sabino, Alexandre Tafuri, Angélica Alves Lima
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Medical Genetics
Subjects:
HPV
Cervical Cancer
SNP
MTHFR C677T polymorphism
Folate metabolism
Online Access:http://link.springer.com/article/10.1186/s12881-019-0831-x

Internet

http://link.springer.com/article/10.1186/s12881-019-0831-x

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