A Preliminary Study of Microsatellite Instability Analysis in Different Genotypes of P53 Codon 72 in Breast Invasive Ductal Carcinomas
Background:The polymorphic variants at codon 72 of the p53 gene, encoding either proline or arginine at residue 72,produce marked change in the structure of p53.From the evidence that the DNAmismatch repair system and p53 interact to maintain genomic integrity, we hypothesized that the codon 72 vari...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Iran University of Medical Sciences
2009-08-01
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| Series: | Medical Journal of The Islamic Republic of Iran |
| Subjects: | |
| Online Access: | http://mjiri.tums.ac.ir/browse.php?a_code=A-10-1-65&slc_lang=en&sid=1 |