Simple and effective generation of transgene-free induced pluripotent stem cells using an auto-erasable Sendai virus vector responding to microRNA-302

Simple and effective generation of transgene-free induced pluripotent stem cells using an auto-erasable Sendai virus vector responding to microRNA-302

Transgene-free induced pluripotent stem cells (iPSCs) are valuable for both basic research and potential clinical applications. We previously reported that a replication-defective and persistent Sendai virus (SeVdp) vector harboring four reprogramming factors (SeVdp-iPS) can efficiently induce gener...

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Bibliographic Details
Main Authors: Ken Nishimura, Manami Ohtaka, Hitomi Takada, Akira Kurisaki, Nhi Vo Kieu Tran, Yen Thi Hai Tran, Koji Hisatake, Masayuki Sano, Mahito Nakanishi
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Stem Cell Research
Subjects:
Sendai virus
Cell reprogramming
Induced pluripotent stem cell
MicroRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506117301113

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http://www.sciencedirect.com/science/article/pii/S1873506117301113

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