The impact of global and local Polynesian genetic ancestry on complex traits in Native Hawaiians.

Epidemiological studies of obesity, Type-2 diabetes (T2D), cardiovascular diseases and several common cancers have revealed an increased risk in Native Hawaiians compared to European- or Asian-Americans living in the Hawaiian islands. However, there remains a gap in our understanding of the genetic...

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Bibliographic Details
Main Authors: Hanxiao Sun, Meng Lin, Emily M Russell, Ryan L Minster, Tsz Fung Chan, Bryan L Dinh, Take Naseri, Muagututi'a Sefuiva Reupena, Annette Lum-Jones, Samoan Obesity, Lifestyle, and Genetic Adaptations (OLaGA) Study Group, Iona Cheng, Lynne R Wilkens, Loïc Le Marchand, Christopher A Haiman, Charleston W K Chiang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-02-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009273