The cost of virulence: retarded growth of Salmonella Typhimurium cells expressing type III secretion system 1.

Virulence factors generally enhance a pathogen's fitness and thereby foster transmission. However, most studies of pathogen fitness have been performed by averaging the phenotypes over large populations. Here, we have analyzed the fitness costs of virulence factor expression by Salmonella enter...

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Bibliographic Details
Main Authors: Alexander Sturm, Matthias Heinemann, Markus Arnoldini, Arndt Benecke, Martin Ackermann, Matthias Benz, Jasmine Dormann, Wolf-Dietrich Hardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC3145796?pdf=render