Role of stromal activin A in human pancreatic cancer and metastasis in mice

Abstract Pancreatic ductal adenocarcinoma (PDAC) has extensive stromal involvement and remains one of the cancers with the highest mortality rates. Activin A has been implicated in colon cancer and its stroma but its role in the stroma of PDAC has not been elucidated. Activin A expression in cancer...

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Bibliographic Details
Main Authors: Georgina Mancinelli, Carolina Torres, Nancy Krett, Jessica Bauer, Karla Castellanos, Ron McKinney, David Dawson, Grace Guzman, Rosa Hwang, Sam Grimaldo, Paul Grippo, Barbara Jung
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87213-y