Targeting PI3K/Akt/Nrf2 pathway by glabridin alleviates acetaminophen-induced hepatic injury in rats

Acetaminophen (APAP) induced liver injury is a leading cause for drug-induced liver damage. Glabridin is an isoflavonoid that is reported to possess anti-inflammatory and oxidative stress preventing effects. The aim of this study was to evaluate the protective effects of glabridin against APAP-induc...

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Bibliographic Details
Main Authors: Hucheng Ma, Haozhen Ren, Jun Wang, Xianwen Yuan, Xinyu Wu, Xiaolei Shi
Format: Article
Language:English
Published: Elsevier 2021-02-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535220305293