TLR2 mediates recognition of live Staphylococcus epidermidis and clearance of bacteremia.

Staphylococcus epidermidis (SE) is a nosocomial pathogen that causes catheter-associated bacteremia in the immunocompromised, including those at the extremes of age, motivating study of host clearance mechanisms. SE-derived soluble components engage TLR2; but additional signaling pathways have also...

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Bibliographic Details
Main Authors: Tobias Strunk, Melanie R Power Coombs, Andrew J Currie, Peter Richmond, Douglas T Golenbock, Liat Stoler-Barak, Leighanne C Gallington, Michael Otto, David Burgner, Ofer Levy
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2852418?pdf=render