Lack of innate interferon responses during SARS coronavirus infection in a vaccination and reinfection ferret model.

Lack of innate interferon responses during SARS coronavirus infection in a vaccination and reinfection ferret model.

In terms of its highly pathogenic nature, there remains a significant need to further define the immune pathology of SARS-coronavirus (SARS-CoV) infection, as well as identify correlates of immunity to help develop vaccines for severe coronaviral infections. Here we use a SARS-CoV infection-reinfect...

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Bibliographic Details
Main Authors: Mark J Cameron, Alyson A Kelvin, Alberto J Leon, Cheryl M Cameron, Longsi Ran, Luoling Xu, Yong-Kyu Chu, Ali Danesh, Yuan Fang, Qianjun Li, Austin Anderson, Ronald C Couch, Stephane G Paquette, Ndingsa G Fomukong, Otfried Kistner, Manfred Lauchart, Thomas Rowe, Kevin S Harrod, Colleen B Jonsson, David J Kelvin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3454321?pdf=render

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