Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction

Potentiating TMEM16A does not stimulate airway mucus secretion or bronchial and pulmonary arterial smooth muscle contraction

Abstract The calcium‐activated chloride channel (CaCC) TMEM16A enables chloride secretion across several transporting epithelia, including in the airways. Additional roles for TMEM16A have been proposed, which include regulating mucus production and secretion and stimulating smooth muscle contractio...

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Bibliographic Details
Main Authors: Henry Danahay, Roy Fox, Sarah Lilley, Holly Charlton, Kathryn Adley, Lee Christie, Ejaz Ansari, Camille Ehre, Alexis Flen, Michael J. Tuvim, Burton F. Dickey, Colin Williams, Sarah Beaudoin, Stephen P Collingwood, Martin Gosling
Format: Article
Language:English
Published: Wiley 2020-08-01
Series:FASEB BioAdvances
Subjects:
Anoctamin‐1
bronchoconstriction
ETX001
mucin
vasoconstriction
Online Access:https://doi.org/10.1096/fba.2020-00035

Internet

https://doi.org/10.1096/fba.2020-00035

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