HMGA2 Contributes to Distant Metastasis and Poor Prognosis by Promoting Angiogenesis in Oral Squamous Cell Carcinoma

HMGA2 Contributes to Distant Metastasis and Poor Prognosis by Promoting Angiogenesis in Oral Squamous Cell Carcinoma

The highly malignant phenotype of oral squamous cell carcinoma (OSCC), including the presence of nodal and distant metastasis, reduces patient survival. High-mobility group A protein 2 (HMGA2) is a non-histone chromatin factor that is involved in advanced malignant phenotypes and poor prognosis in s...

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Bibliographic Details
Main Authors: Junki Sakata, Akiyuki Hirosue, Ryoji Yoshida, Kenta Kawahara, Yuichiro Matsuoka, Tatsuro Yamamoto, Masafumi Nakamoto, Masatoshi Hirayama, Nozomu Takahashi, Takuya Nakamura, Hidetaka Arita, Hikaru Nakashima, Masashi Nagata, Akimitsu Hiraki, Masanori Shinohara, Hideki Nakayama
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
angiogenesis
HMGA2
metastasis
oral squamous cell carcinoma
prognosis
Online Access:https://www.mdpi.com/1422-0067/20/10/2473

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https://www.mdpi.com/1422-0067/20/10/2473

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