Loss of ID3 drives papillary thyroid cancer metastasis by targeting E47-mediated epithelial to mesenchymal transition

Abstract Papillary thyroid cancer (PTC) is the main histological type of thyroid cancer and accounts for almost all increased cases worldwide. Patients with PTC exhibit a favorable prognosis, but the fact that PTC is often accompanied by a high prevalence of lymph node metastasis (LNM) means that th...

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Bibliographic Details
Main Authors: Sunwang Xu, Caiqin Mo, Junyu Lin, Yixing Yan, Xiaoyu Liu, Kunlin Wu, Huihao Zhang, Youzhi Zhu, Ling Chen, Xiangjin Chen
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-021-00614-w