Apoptosis Induction byHistone Deacetylase Inhibitors in Cancer Cells: Role of Ku70
Histone deacetylases (HDACs) are a group of enzymes that regulate gene transcription by controlling deacetylation of histones and non-histone proteins. Overexpression of HDACs is found in some types of tumors and predicts poor prognosis. Five HDAC inhibitors are approved for the treatment of cutaneo...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-03-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/20/7/1601 |