Modulation of Induced Cytotoxicity of Doxorubicin by Using Apoferritin and Liposomal Cages

Modulation of Induced Cytotoxicity of Doxorubicin by Using Apoferritin and Liposomal Cages

Doxorubicin is an effective chemotherapeutic drug, however, its toxicity is a significant limitation in therapy. Encapsulation of doxorubicin inside liposomes or ferritin cages decreases cardiotoxicity while maintaining anticancer potency. We synthesized novel apoferritin- and liposome-encapsulate...

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Bibliographic Details
Main Authors: Jaromir Gumulec, Michaela Fojtu, Martina Raudenska, Marketa Sztalmachova, Anna Skotakova, Jana Vlachova, Sylvie Skalickova, Lukas Nejdl, Pavel Kopel, Lucia Knopfova, Vojtech Adam, Rene Kizek, Marie Stiborova, Petr Babula, Michal Masarik
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:International Journal of Molecular Sciences
Subjects:
doxorubicin
liposome
apoferritin
cancer
cardiotoxicity
modification
encapsulation
Online Access:http://www.mdpi.com/1422-0067/15/12/22960

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http://www.mdpi.com/1422-0067/15/12/22960

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