Treatment monitoring of colorectal cancer by integrated analysis of plasma concentration and sequencing of circulating tumor DNA

Treatment monitoring of colorectal cancer by integrated analysis of plasma concentration and sequencing of circulating tumor DNA

Abstract Circulating cell-free DNA (cfDNA) analysis is an important tool for cancer monitoring. The patient-specific mutations identified in colorectal cancer (CRC) tissues are usually used to design the cfDNA analysis. Despite high specificity in predicting relapse, the sensitivity in most studies...

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Bibliographic Details
Main Authors: Yu-Min Yeh, Peng-Chan Lin, Chung-Ta Lee, Shang-Hung Chen, Bo-Wen Lin, Shao-Chieh Lin, Po-Chuan Chen, Ren-Hao Chan, Meng-Ru Shen
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Molecular Cancer
Subjects:
Colorectal cancer
Circulating cell-free DNA
Cell-free DNA concentration
Molecular barcode
Next-generation sequencing
Online Access:http://link.springer.com/article/10.1186/s12943-020-01273-8

Internet

http://link.springer.com/article/10.1186/s12943-020-01273-8

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