Effects of In Utero Exposure to Di-n-Butyl Phthalate on Testicular Development in Rat

Effects of In Utero Exposure to Di-n-Butyl Phthalate on Testicular Development in Rat

Humans are inevitably exposed to ubiquitous phthalate esters (PAEs). In utero exposure to di-n-butyl phthalate (DBP) induces abnormal development of the testis and reproductive tract in male offspring, which correspond closely with the human condition of testicular dysgenesis syndrome (TDS)-like syn...

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Bibliographic Details
Main Authors: Tan Ma, Xiaoqin Yin, Ruitong Han, Jie Ding, Huan Zhang, Xiaodong Han, Dongmei Li
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:International Journal of Environmental Research and Public Health
Subjects:
prenatal DBP exposure
testicular cells
ras related dexamethasone induced 1 (Rasd1)
MEK1/2
Bcl-2
Bax
cell proliferation
apoptosis
Online Access:https://www.mdpi.com/1660-4601/14/10/1284

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https://www.mdpi.com/1660-4601/14/10/1284

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