Losartan reduces sympathetic nerve outflow from the brain of rats with chronic renal failure

Sympathetic nervous system (SNS) activity, measured by norepinephrine (NE) turnover rate, was greater in the posterior hypothalamic (PH) nuclei, the paraventricular nuclei (PVN), and the locus coeruleus (LC) of 5/6 nephrectomised (CRF) rats than of control rats. NE secretion from the PH was also gre...

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Bibliographic Details
Main Authors: Vito M Campese, Shaohua Ye, Rex H Truong, Michael Gamburd
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2000-06-01
Series:Journal of the Renin-Angiotensin-Aldosterone System
Online Access:https://doi.org/10.3317/jraas.2000.026