Caspase-3 Mediated Cell Death in the Normal Development of the Mammalian Cerebellum

Caspase-3, onto which there is a convergence of the intrinsic and extrinsic apoptotic pathways, is the main executioner of apoptosis. We here review the current literature on the intervention of the protease in the execution of naturally occurring neuronal death (NOND) during cerebellar development....

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Bibliographic Details
Main Authors: Laura Lossi, Claudia Castagna, Adalberto Merighi
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/19/12/3999