Benzo(a)pyrene induced p53 mediated male germ cell apoptosis: Synergistic protective effects of curcumin and resveratrol

Benzo(a)pyrene induced p53 mediated male germ cell apoptosis: Synergistic protective effects of curcumin and resveratrol

B(a)P (Benzo(a)pyrene) is an environmental toxicant that induces male germ cell apoptosis. Curcumin and resveratrol are phytochemicals with cytoprotective and anti-oxidative properties. At the same time resveratrol is also a natural Aryl hydrocarbon Receptor (AhR) antagonist. Our present study in is...

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Bibliographic Details
Main Authors: Bhaswati Banerjee, Supriya Chakaraborty, Debidas Ghosh, Sanghamitra Raha, Parimal C Sen, Kuladip Jana
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-08-01
Series:Frontiers in Pharmacology
Subjects:
Apoptosis
AhR
germ cell
MAPK
B(a)P
p53.
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00245/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphar.2016.00245/full

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