The Human Pendrin Promoter Contains two N4 GAS Motifs with Different Functional Relevance

The Human Pendrin Promoter Contains two N4 GAS Motifs with Different Functional Relevance

Background: Pendrin, an anion exchanger associated with the inner ear, thyroid and kidney, plays a significant role in respiratory tissues and diseases, where its expression is increased following IL-4 and IL-13 exposure. The mechanism leading to increased pendrin expression is in part due to bindin...

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Bibliographic Details
Main Authors: Simone Vanoni, Charity Nofziger, Silvia Dossena, Selma M. Soyal, Wolfgang Patsch, Paolo Plevani, Albert Duschl, Markus Paulmichl
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2013-12-01
Series:Cellular Physiology and Biochemistry
Subjects:
Interleukin 4
Cytokine
ChIP
SLC26A4
STAT6
Online Access:http://www.karger.com/Article/FullText/356642

Internet

http://www.karger.com/Article/FullText/356642

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