Examining the causal association between 25-hydroxyvitamin D and caries in children and adults: a two-sample Mendelian randomization approach [version 2; peer review: 2 approved]

Background: Prior observational studies have reported that higher levels of vitamin D are associated with decreased caries risk in children. However, these studies are prone to bias and confounding so do not provide causal inference. Genetic variants associated with a risk factor of interest can be...

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Bibliographic Details
Main Authors: Serena A. Dodhia, Nicola X. West, Steven J. Thomas, Nicholas J. Timpson, Ingegerd Johansson, Pernilla Lif Holgerson, Tom Dudding, Simon Haworth
Format: Article
Language:English
Published: Wellcome 2021-07-01
Series:Wellcome Open Research
Online Access:https://wellcomeopenresearch.org/articles/5-281/v2