Basic Concepts in G-Protein-Coupled Receptor Homo- and Heterodimerization

Until recently, heptahelical G-protein-coupled receptors (GPCRs) were considered to be expressed as monomers on the cell surface of neuronal and non-neuronal cells. It is now becoming evident that this view must be overtly changed since these receptors can form homodimers, heterodimers, and higher-o...

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Bibliographic Details
Main Authors: Rafael Franco, Vicent Casadó, Antoni Cortés, Carla Ferrada, Josefa Mallol, Amina Woods, Carme Lluis, Enric I. Canela, Sergi Ferré
Format: Article
Language:English
Published: Hindawi Limited 2007-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2007.197