Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.

Nicotinamide exacerbates hypoxemia in ventilator-induced lung injury independent of neutrophil infiltration.

BACKGROUND:Ventilator-induced lung injury is a form of acute lung injury that develops in critically ill patients on mechanical ventilation and has a high degree of mortality. Nicotinamide phosphoribosyltransferase is an enzyme that is highly upregulated in ventilator-induced lung injury and exacerb...

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Bibliographic Details
Main Authors: Heather D Jones, Jeena Yoo, Timothy R Crother, Pierre Kyme, Anat Ben-Shlomo, Ramtin Khalafi, Ching W Tseng, William C Parks, Moshe Arditi, George Y Liu, Kenichi Shimada
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4395431?pdf=render

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http://europepmc.org/articles/PMC4395431?pdf=render

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