Pre-clinical modelling of rectal cancer to develop novel radiotherapy-based treatment strategies

Pre-operative chemoradiotherapy reduces local recurrence rates in locally advanced rectal cancer. 10-20% of patients undergo complete response to chemoradiotherapy, however, many patients show no response. The mechanisms underlying this are poorly understood; identifying molecular and immunological...

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Bibliographic Details
Main Authors: Michael A. Gillespie, Colin W. Steele, Tamsin R.M. Lannagan, Owen J. Sansom, Campbell S.D. Roxburgh
Format: Article
Language:English
Published: PAGEPress Publications 2021-06-01
Series:Oncology Reviews
Subjects:
Online Access:https://oncologyreviews.org/site/article/view/511