Glioblastoma Organoids: Pre-Clinical Applications and Challenges in the Context of Immunotherapy

Malignant brain tumors remain uniformly fatal, even with the best-to-date treatment. For Glioblastoma (GBM), the most severe form of brain cancer in adults, the median overall survival is roughly over a year. New therapeutic options are urgently needed, yet recent clinical trials in the field have b...

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Bibliographic Details
Main Authors: Eliane Klein, Ann-Christin Hau, Anaïs Oudin, Anna Golebiewska, Simone P. Niclou
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-12-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.604121/full