A New Method to Quantify Ifosfamide Blood Levels Using Dried Blood Spots and UPLC-MS/MS in Paediatric Patients with Embryonic Solid Tumours.

A New Method to Quantify Ifosfamide Blood Levels Using Dried Blood Spots and UPLC-MS/MS in Paediatric Patients with Embryonic Solid Tumours.

Ifosfamide blood concentrations are necessary to monitor its therapeutic response, avoiding any adverse effect. We developed and validated an analytical method by UPLC-MS/MS to quantify ifosfamide in dried blood spots (DBS). Blood samples were collected on Whatman 903® filter paper cards. Five 3 mm...

Full description

Bibliographic Details
Main Authors: Luz-María Torres, Liliana Rivera-Espinosa, Juan L Chávez-Pacheco, Carlos F Navas, Joel A Demetrio, Radamés Alemón-Medina, Francisca Trujillo, Martín Pérez, Martha M Zapata, Rocío Cárdenas, Citlaltepetl Salinas, Arnoldo Aquino, Rafael Velázquez-Cruz, Manuel-de-Jesús Castillejos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4657950?pdf=render

Internet

http://europepmc.org/articles/PMC4657950?pdf=render

Similar Items