Neutrophil gelatinase-associated lipocalin (NGAL) predicts response to neoadjuvant chemotherapy and clinical outcome in primary human breast cancer.

Neutrophil gelatinase-associated lipocalin (NGAL) predicts response to neoadjuvant chemotherapy and clinical outcome in primary human breast cancer.

In our previous work we showed that NGAL, a protein involved in the regulation of proliferation and differentiation, is overexpressed in human breast cancer (BC) and predicts poor prognosis. In neoadjuvant chemotherapy (NACT) pathological complete response (pCR) is a predictor for outcome. The aim o...

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Bibliographic Details
Main Authors: Antonia Sophie Wenners, Keyur Mehta, Sibylle Loibl, Hyerim Park, Berit Mueller, Norbert Arnold, Sigrid Hamann, Joerg Weimer, Beyhan Ataseven, Silvia Darb-Esfahani, Christian Schem, Christoph Mundhenke, Fariba Khandan, Christoph Thomssen, Walter Jonat, Hans-Juergen Holzhausen, Gunther von Minckwitz, Carsten Denkert, Maret Bauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3467272?pdf=render

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http://europepmc.org/articles/PMC3467272?pdf=render

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