Insulin signaling and reduced glucocorticoid receptor activity attenuate postprandial gene expression in liver.

Hepatic circadian gene transcription is tightly coupled to feeding behavior, which has a profound impact on metabolic disorders associated with diet-induced obesity. Here, we describe a genomics approach to uncover mechanisms controlling hepatic postprandial gene expression. Combined transcriptomic...

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Bibliographic Details
Main Authors: Adrija Kalvisa, Majken S Siersbæk, Stine M Præstholm, Line J L Christensen, Ronni Nielsen, Oliver Stohr, Sabine Vettorazzi, Jan Tuckermann, Morris White, Susanne Mandrup, Lars Grøntved
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.2006249