Mesenchymal stromal cells derived from the bone marrow of acute lymphoblastic leukemia patients show altered BMP4 production: correlations with the course of disease.

The relevance of tumor microenvironment for the development and progression of tumor cells in hematological malignancies has been extensively reported. Identification of factors involved in the information exchange between the malignant cells and the bone marrow mesenchymal stem cells (BM-MSCs) and...

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Main Authors: Ángeles Vicente López, Miriam Nohemí Vázquez García, Gustavo J Melen, Ana Entrena Martínez, Isabel Cubillo Moreno, Javier García-Castro, Manuel Ramírez Orellana, Agustín Gregorio Zapata González
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3882230?pdf=render