The anthelmintic drug niclosamide induces apoptosis, impairs metastasis and reduces immunosuppressive cells in breast cancer model.

Breast carcinoma is the most common female cancer with considerable metastatic potential. Discovery of new therapeutic approaches for treatment of metastatic breast cancer is still needed. Here, we reported our finding with niclosamide, an FDA approved anthelmintic drug. The potency of niclosamide o...

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Bibliographic Details
Main Authors: Tinghong Ye, Ying Xiong, Yupeng Yan, Yong Xia, Xuejiao Song, Li Liu, Deliang Li, Ningyu Wang, Lidan Zhang, Yongxia Zhu, Jun Zeng, Yuquan Wei, Luoting Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3885752?pdf=render