Neurodegenerative changes in early- and late-onset cognitive impairment with and without brain amyloidosis

Abstract Background A substantial number of patients clinically diagnosed with Alzheimer’s disease do not harbor amyloid pathology. We analyzed the presence and extent of tau deposition and neurodegeneration in amyloid-positive (AD) and amyloid-negative (nonAD) ADNI subjects while also taking into a...

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Bibliographic Details
Main Authors: Eddie C. Stage, Diana Svaldi, Meredith Phillips, Victor Hugo Canela, Tugce Duran, Naira Goukasian, Shannon L. Risacher, Andrew J. Saykin, Liana G. Apostolova, for the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Alzheimer’s Research & Therapy
Subjects:
AD
MRI
PET
Online Access:http://link.springer.com/article/10.1186/s13195-020-00647-w