Substrate transport and anion permeation proceed through distinct pathways in glutamate transporters

Advances in structure-function analyses and computational biology have enabled a deeper understanding of how excitatory amino acid transporters (EAATs) mediate chloride permeation and substrate transport. However, the mechanism of structural coupling between these functions remains to be established...

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Bibliographic Details
Main Authors: Mary Hongying Cheng, Delany Torres-Salazar, Aneysis D Gonzalez-Suarez, Susan G Amara, Ivet Bahar
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-06-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/25850