The endocrine disruptor mono-(2-ethylhexyl)phthalate promotes adipocyte differentiation and induces obesity in mice

The endocrine disruptor mono-(2-ethylhexyl)phthalate promotes adipocyte differentiation and induces obesity in mice

The environmental obesogen hypothesis proposes that exposure to endocrine disruptors during developmental ‘window’ contributes to adipogenesis and the development of obesity. MEHP [mono-(2-ethylhexyl) phthalate], a metabolite of the widespread plasticizer DEHP [di-(2-ethylhexyl...

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Bibliographic Details
Main Authors: Chanjuan Hao, Xuejia Cheng, Hongfei Xia, Xu Ma
Format: Article
Language:English
Published: Portland Press, Biochemical Society 2012-10-01
Series:Bioscience Reports
Subjects:
adipogenesis
mono(2-ethylhexyl) phthalate (MEHP)
obesity
perinatal exposure
peroxisome proliferator-activated receptor γ
Online Access:http://www.bioscirep.org/bsr/032/0619/bsr0320619.htm

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http://www.bioscirep.org/bsr/032/0619/bsr0320619.htm

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