Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer

Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer

Abstract Background Metastasis is the major cause of morbidity and mortality in patients with epithelial ovarian cancer (EOC), however the mechanisms that underline this process are poorly understood. Collagen triple helix repeat containing-1 (CTHRC1) is a 28-kDa secreted protein reported to be invo...

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Bibliographic Details
Main Authors: Biying Guo, Huan Yan, Luying Li, Kemin Yin, Fang Ji, Shu Zhang
Format: Article
Language:English
Published: BMC 2017-10-01
Series:Journal of Ovarian Research
Subjects:
CTHRC1
Ovarian cancer
Metastasis
Integrin/FAK signaling
Online Access:http://link.springer.com/article/10.1186/s13048-017-0358-8

Internet

http://link.springer.com/article/10.1186/s13048-017-0358-8

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