Biomarkers representing key aging-related biological pathways are associated with subclinical atherosclerosis and all-cause mortality: The Framingham Study.

<h4>Background</h4>Increased oxidative stress, leukocyte telomere length (LTL) shortening, endothelial dysfunction, and lower insulin-like growth factor (IGF)-1 concentrations reflect key molecular mechanisms of aging. We hypothesized that biomarkers representing these pathways are assoc...

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Bibliographic Details
Main Authors: Cecilia Castro-Diehl, Rachel Ehrbar, Vanesa Obas, Albin Oh, Ramachandran S Vasan, Vanessa Xanthakis
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0251308