Implication of urinary complement factor H in the progression of immunoglobulin A nephropathy.

After activation, the complement system is involved in the pathogenesis of Immunoglobulin A nephropathy (IgAN). Complement factor H (CFH) is a crucial inhibitory factor of the alternative pathway of the complement system. The study investigated the effects of urinary CFH levels on IgAN progression.A...

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Bibliographic Details
Main Authors: Maojing Liu, Yuqing Chen, Jingjing Zhou, Ying Liu, Fengmei Wang, Sufang Shi, Yanfeng Zhao, Suxia Wang, Lijun Liu, Jicheng Lv, Hong Zhang, Minghui Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4452759?pdf=render