Streamlined copper defenses make Bordetella pertussis reliant on custom-made operon

Alex Rivera-Millot et al. investigate copper homeostasis in the whooping cough agent Bordetella pertussis, which has a single copper defense mechanism via a metallochaperone diverted for copper passivation and two peroxide detoxification enzymes. This study demonstrates that copper up-regulates the...

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Bibliographic Details
Main Authors: Alex Rivera-Millot, Stéphanie Slupek, Jonathan Chatagnon, Gauthier Roy, Jean-Michel Saliou, Gabriel Billon, Véronique Alaimo, David Hot, Sophie Salomé-Desnoulez, Camille Locht, Rudy Antoine, Françoise Jacob-Dubuisson
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-020-01580-2