Thymoquinone Promotes Pancreatic Cancer Cell Death and Reduction of Tumor Size through Combined Inhibition of Histone Deacetylation and Induction of Histone Acetylation

Pancreatic ductal adenocarcinoma (PDAC) is virtually therapy-resistant. As noninvasive lesions progress to malignancy, the precursor period provides a window for cancer therapies that can interfere with neoplastic progression. Thymoquinone (Tq), a major bioactive component of essential oil from Nige...

Full description

Bibliographic Details
Main Authors: Daniel Relles, Galina I. Chipitsyna, Qiaoke Gong, Charles J. Yeo, Hwyda A. Arafat
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Advances in Preventive Medicine
Online Access:http://dx.doi.org/10.1155/2016/1407840