Prostaglandins and Mucosal Defensive Mechanisms
The first line of mucosa! defence includes the juxtamucosal unstirred layer/pH gradient and the apical surface of the luminal epithelial cells. Many damaging agents, including nonsteroidal anti-inflammatory drugs (NSAIDs), can overwhelm these defences and destroy extensive regions of the luminal epi...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
1990-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/1990/217689 |