Prostaglandins and Mucosal Defensive Mechanisms

The first line of mucosa! defence includes the juxtamucosal unstirred layer/pH gradient and the apical surface of the luminal epithelial cells. Many damaging agents, including nonsteroidal anti-inflammatory drugs (NSAIDs), can overwhelm these defences and destroy extensive regions of the luminal epi...

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Bibliographic Details
Main Authors: Gerald P Morris, Todd E Williamson, Taimi T Hynna
Format: Article
Language:English
Published: Hindawi Limited 1990-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/1990/217689

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