Alpha-naphthoflavone attenuates non-alcoholic fatty liver disease in oleic acid-treated HepG2 hepatocytes and in high fat diet-fed mice

Non-alcoholic fatty liver disease (NAFLD) is a chronic liver disease. The literature suggests that the aryl hydrocarbon receptor (AHR) may be a key player in the pathogenesis of NAFLD, and it can modulate the synthesis of cytochrome P450 1A1 (CYP1A1) and tumor necrosis factor-α (TNF-α). Previous stu...

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Bibliographic Details
Main Authors: Hongguang Xia, Xiangyu Zhu, Xiaoyan Zhang, Haiyan Jiang, Biao Li, Zhihao Wang, Dalang Li, Yong Jin
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332219314775