PESM: predicting the essentiality of miRNAs based on gradient boosting machines and sequences

Abstract Background MicroRNAs (miRNAs) are a kind of small noncoding RNA molecules that are direct posttranscriptional regulations of mRNA targets. Studies have indicated that miRNAs play key roles in complex diseases by taking part in many biological processes, such as cell growth, cell death and s...

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Bibliographic Details
Main Authors: Cheng Yan, Fang-Xiang Wu, Jianxin Wang, Guihua Duan
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-3426-9