Identification of a putative nuclear localization signal in the tumor suppressor maspin sheds light on its nuclear import regulation

The tumor suppressor activity of maspin (mammary serine protease inhibitor) has been associated with its nuclear localization. In this study we explore the regulation of maspin nuclear translocation. An in vitro nuclear import assay suggested that maspin can passively enter the nucleus. However, in ...

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Bibliographic Details
Main Authors: Jeffrey Reina, Lixin Zhou, Marcos R. M. Fontes, Nelly Panté, Nathalie Cella
Format: Article
Language:English
Published: Wiley 2019-07-01
Series:FEBS Open Bio
Subjects:
Online Access:https://doi.org/10.1002/2211-5463.12626